Methylphenidate and Autism
Ranking:
Studies and Trials
This section provides details of scientific studies into the effectiveness of this intervention for autistic people which have been published in English-language, peer-reviewed journals.
If you know of any other publications we should list on this page please email info@informationautism.org
Please note that we are unable to supply publications unless we are listed as the publisher. However, if you are a UK resident you may be able to obtain them from your local public library, your college library or direct from the publisher.
Related Studies and Trials
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Akyol Ardic Ü.
et al.
(2017)
Altered response with methylphenidate to ADHD-like symptoms in pervasive developmental disorder: does CES-1 enzyme gene polymorphism have a role
European Child and Adolescent Psychiatry.
28(2),
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Birmaher B., Quintana H., Greenhill L. L. (1988)
Brief report: Methylphenidate treatment of hyperactive autistic children.
Journal of the American Academy of Child and Adolescent Psychiatry.
27(2),
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DiMartino A.
et al.
(2004)
Methylphenidate for pervasive developmental disorders: safety and efficacy of acute single dose test and ongoing therapy: an open-pilot study.
Journal of Child and Adolescent Psychopharmacology.
14(2),
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Ghuman J. K.
et al.
(2009)
Randomized, placebo-controlled, crossover study of methylphenidate for attention-deficit hyperactivity disorder symptoms in preschoolers with developmental disorders.
Journal of Child and Adolescent Psychopharmacology.
19(4),
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Golubchik P., Rapaport M., Weizman A. (2017)
The effect of methylphenidate on anxiety and depression symptoms in patients with Asperger syndrome and comorbid attention deficit-hyperactivity disorder.
International Clinical Psychopharmacology.
32(4),
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Handen B. L., Johnson C. R., Lubetsky M. J. (2000)
Efficacy of methylphenidate among children with autism and symptoms of attention-deficit hyperactivity disorder.
Journal of Autism and Developmental Disorders.
30(3),
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Hoshino Y.
et al.
(1977)
The effects of methylphenidate on early infantile autism and its relation to serum serotonin levels.
Folia Psychiatrica et Neurologica Japonica.
31(4),
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Jahromi L. B.
et al.
(2009)
Positive effects of methylphenidate on social communication and self-regulation in children with pervasive developmental disorders and hyperactivity.
Journal of Autism and Developmental Disorders.
39(3),
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Kim S.
et al.
(2017)
Dose-response effects of long-acting liquid methylphenidate in children with attention deficit-hyperactivity disorder (ADHD) and autism spectrum disorder (ASD): a pilot study.
Journal of Autism and Developmental Disorders.
47(8),
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Nickels K.
et al.
(2008)
Stimulant medication treatment of target behaviors in children with autism: a population-based study.
Journal of Developmental and Behavioral Pediatrics.
29(2),
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Pearson D. A.
et al.
(2013)
Effects of extended release methylphenidate treatment on ratings of attention-deficit hyperactivity disorder (ADHD) and associated behavior in children with autism spectrum disorders and ADHD symptoms.
Journal of Child and Adolescent Psychopharmacology.
23(5),
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Posey D. J.
et al.
(2007)
Positive effects of methylphenidate on inattention and hyperactivity in pervasive developmental disorders: an analysis of secondary measures.
Biological Psychiatry.
61(4),
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Quintana H.
et al.
(1995)
Use of methylphenidate in the treatment of children with autistic disorder.
Journal of Autism and Developmental Disorders.
25(3),
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Research Units on Pediatric Psychopharmacology (RUPP) Autism Network (2005)
Randomized, controlled, crossover trial of methylphenidate in pervasive developmental disorders with hyperactivity.
Archives of General Psychiatry.
Research Units on Pediatric Psychopharmacology (RUPP) Autism Network
62(11),
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Roy M.
et al.
(2009)
Effective methylphenidate treatment of an adult Aspergers syndrome and a comorbid ADHD: A clinical investigation with fMRI.
Journal of Attention Disorders.
12(4),
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Santosh P. J.
et al.
(2006)
Impact of comorbid autism spectrum disorders on stimulant response in children with attention deficit hyperactivity disorder: a retrospective and prospective effectiveness study.
Child: Care, Health and Development.
32(5),
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Scahill L.
et al.
(2017)
Using a patient-centered outcome measure to test methylphenidate versus placebo in children with autism spectrum disorder.
Journal of Child and Adolescent Psychopharmacology.
27(2),
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Simonoff E.
et al.
(2013)
Randomized controlled double-blind trial of optimal dose methylphenidate in children and adolescents with severe attention deficit hyperactivity disorder and intellectual disability.
Journal of Child Psychology and Psychiatry.
54(5),
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Stigler K. A.
et al.
(2004)
A naturalistic retrospective analysis of psychostimulants in pervasive developmental disorders.
Journal of Child and Adolescent Psychopharmacology.
14(1),
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- Updated
- 17 Jun 2022
- Last Review
- 01 Dec 2018
- Next Review
- 01 Sep 2024