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Hyperbaric Therapy and Autism Ranking: Strong negative evidence

Current Research

We have identified nine scientific studies of hyperbaric therapy in peer-reviewed journals published in English.

These trials included more than 200 individuals aged from 3 to 16. These individuals included people with autistic disorder, Asperger syndrome and pervasive developmental disorder - not otherwise specified.

  • Five of the studies (Bent S. et al. (2012); Chungpaibulpatana J. et al. (2008); Rossignol D. A. Rossignol L. W. (2006); Rossignol D. A. et al. (2009); Rossignol D. A. et al. (2007) reported benefits of various kinds. For example, Rossignol D. A. et al. (2009) reported “Children with autism who received hyperbaric treatment at 1.3 atm and 24% oxygen for 40 hourly sessions had significant improvements in overall functioning, receptive language, social interaction, eye contact, and sensory/cognitive awareness compared to children who received slightly pressurized room air.”
  • Four studies (Granpeesheh D. et al. (2010); Jepson B. et al. (2011); Lerman D. C. et al. (2008); Sampanthavivat M. et al. (2012) reported inconsistent effects, suggesting that there were no benefits. For example, (Granpeesheh D. et al. (2010) reported  “The present study demonstrates that HBOT delivered at 24% oxygen at 1.3 atmospheric pressure does not result in a clinically significant improvement of the symptoms of Autistic Disorder. “
Updated
17 Jun 2022
Last Review
01 Sep 2016
Next Review
01 Dec 2022