logo

Secretin and Autism Ranking: Mildly Hazardous Very strong negative evidence

Aims and Claims

Aims

The main medical use of secretin is as a diagnostic tool in various disorders of the pancreas. However some people believe that secretin can be used to treat gastrointestinal problems (such as constipation and diarrhoea) in autistic people. They also believe that treating those gastrointestinal problems will lead to improvements in other areas (such as sociability, speech, and sleep).

Claims 

There have been various claims made for the use of secretin as an intervention for autistic people. For example, 

  • Horvath et al (1998) claimed “significant amelioration of the children was observed, as was a dramatic improvement in their behavior, manifested by improved eye contact, alertness, and expansion of expressive language”
  • Lonsdale and Shamberger (2000) claimed that approximately half of the participants treated in their study showed “minor to major behavioral and/or bowel function improvement”.
  • Robinson (2001) claimed that approximately half of the participants treated in his study improved in one way or another (such as being more relaxed, being more communicative or being less aggressive).
Updated
16 Jun 2022
Last Review
01 Dec 2018
Next Review
01 Aug 2024