There is some evidence of a link between immune deficiency disorders and some autistic people but the nature of that link is unclear. For example, in 2016, Mandy and Lai noted
“There is now increasing evidence suggesting a central role of immune dysregulation in ASC. Neuro-immune processes are not only key to the neurobiological characteristics of individuals with ASC themselves but such processes may also play a contributing’ role in atypical neurodevelopment as early as the gestational period and may explain the pathogenesis of the autism phenotype in a subgroup of individuals”.