Immune Globulins and Autism Ranking:

History

According to Sewell et al (2014), the use of immunoglobulins as a treatment for immunological disorders began in the 1940s.

“Plasma fractionation for the preparation of albumin, clotting factors, and subcutaneous/intramuscular Ig began in the 1940s; industrial scale plasma fractionation started in 1943. Intravenous Ig (IVIg) was introduced in the early 1970s and became the driving market force in the 1990s when plasma-derived Factor VIII and Factor IX were increasingly replaced by recombinant products”. 

We have yet to identify by whom and when the use of immune globulin for autistic people was first suggested but we think it is likely to have been in the late 1980s.  The first study to appear in a peer-reviewed journal was Gupta et al. (1996).

Updated

16 Jun 2022

Last Review

31 May 2018

Next Review

01 Jun 2024